Quantitative
Methods in Bioinformatics
Course Information
This course is
cross listed as BIOL 337, STAT 337, and STAT 437
 
Homework: UG Student Groups 
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Class Notes:
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Some Articles:
1997 Scientific American 
QTLs Wu & Casella
Useful Websites: 
Course Syllabus 
Ends-Space Free Notes 
Course Paper-Project 
Steve
Kachman's Bioinformatics notes 
Wellcome Trust Sanger Institute
PCA and Cluster Analysis for Mammals on p.517 
Images (protein synthesis etc.) 
 Two
DNA sequences from old textbook (p.1) - 
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   g  | 
  
   a  | 
  
   g  | 
  
   a  | 
  
   c  | 
  
   t  | 
  
   g  | 
  
   t  | 
  
   a  | 
  
   g  | 
  
   a  | 
  
   c  | 
  
   a  | 
  
   g  | 
  
   c  | 
  
   t  | 
  
   a  | 
  
   a  | 
  
   t  | 
  
   g  | 
  
   c  | 
  
   t  | 
  
   a  | 
  
   t  | 
  
   a  | 
 
| 
   g  | 
  
   a  | 
  
   a  | 
  
   c  | 
  
   g  | 
  
   c  | 
  
   c  | 
  
   c  | 
  
   t  | 
  
   a  | 
  
   g  | 
  
   c  | 
  
   c  | 
  
   a  | 
  
   c  | 
  
   g  | 
  
   a  | 
  
   g  | 
  
   c  | 
  
   c  | 
  
   c  | 
  
   t  | 
  
   t  | 
  
   a  | 
  
   t  | 
  
   c  | 
 
 
Two amino acid sequences from old textbook (p.258)-
 
| 
      | 
  
      | 
  
   T  | 
  
   Q  | 
  
   L  | 
  
   A  | 
  
   A  | 
  
   W  | 
  
   C  | 
  
   R  | 
  
   M  | 
  
   T  | 
  
   C  | 
  
   F  | 
  
   E  | 
  
   I  | 
  
   E  | 
  
   C  | 
  
   K  | 
  
   V  | 
 
| 
      | 
  
      | 
  
   R  | 
  
   H  | 
  
   L  | 
  
   D  | 
  
   S  | 
  
   W  | 
  
   R  | 
  
   R  | 
  
   A  | 
  
   S  | 
  
   D  | 
  
   D  | 
  
   A  | 
  
   R  | 
  
   I  | 
  
   E  | 
  
   E  | 
  
   G  | 
 
| 
   Scores  | 
  
   SN  | 
  
   -1  | 
  
   0  | 
  
   4  | 
  
   -2  | 
  
   1  | 
  
   11  | 
  
   -3  | 
  
   5  | 
  
   -1  | 
  
   1  | 
  
   -3  | 
  
   -3  | 
  
   -1  | 
  
   -3  | 
  
   -3  | 
  
   -4  | 
  
   1  | 
  
   -3  | 
 
| 
   Sum   | 
  
   TN  | 
  
   -1  | 
  
   -1  | 
  
   3  | 
  
   1  | 
  
   2  | 
  
   13  | 
  
   10  | 
  
   15  | 
  
   14  | 
  
   15  | 
  
   12  | 
  
   9  | 
  
   8  | 
  
   5  | 
  
   2  | 
  
   -2  | 
  
   -1  | 
  
   -4  | 
 
Graph of cumulative scores for above pair of Amino
Acids